Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association

BACKGROUND: Large cancer genome studies continue to reveal new players in treatment response and tumorigenesis. The discrimination of functional alterations from the abundance of passenger genetic alterations still poses challenges and determines DNA sequence variant selection procedures. Here we ev...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Vossen, David M., Verhagen, Caroline V. M., Grénman, Reidar, Kluin, Roelof J. C., Verheij, Marcel, van den Brekel, Michiel W. M., Wessels, Lodewyk F. A., Vens, Conchita
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224072/
https://ncbi.nlm.nih.gov/pubmed/30408064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206632
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