Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association

BACKGROUND: Large cancer genome studies continue to reveal new players in treatment response and tumorigenesis. The discrimination of functional alterations from the abundance of passenger genetic alterations still poses challenges and determines DNA sequence variant selection procedures. Here we ev...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Vossen, David M., Verhagen, Caroline V. M., Grénman, Reidar, Kluin, Roelof J. C., Verheij, Marcel, van den Brekel, Michiel W. M., Wessels, Lodewyk F. A., Vens, Conchita
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224072/
https://ncbi.nlm.nih.gov/pubmed/30408064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206632
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki