Structure-Based Identification of Potent Natural Product Chemotypes as Cannabinoid Receptor 1 Inverse Agonists

Natural products are an abundant source of potential drugs, and their diversity makes them a rich and viable prospective source of bioactive cannabinoid ligands. Cannabinoid receptor 1 (CB1) antagonists are clinically established and well documented as potential therapeutics for treating obesity, ob...

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Veröffentlicht in:Molecules
Hauptverfasser: Pandey, Pankaj, Roy, Kuldeep K., Liu, Haining, Ma, Guoyi, Pettaway, Sara, Alsharif, Walid F., Gadepalli, Rama S., Rimoldi, John M., McCurdy, Christopher R., Cutler, Stephen J., Doerksen, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222380/
https://ncbi.nlm.nih.gov/pubmed/30322136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102630
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