Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood

The G2019S mutation in leucine-rich repeat kinase 2 (LRRK2) is a prevalent cause of late-onset Parkinson's disease, producing psychiatric and motor symptoms, including depression, that are indistinguishable from sporadic cases. Here we tested how this mutation impacts depression-related behavio...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Matikainen-Ankney, Bridget A., Kezunovic, Nebojsa, Menard, Caroline, Flanigan, Meghan E., Zhong, Yue, Russo, Scott J., Benson, Deanna L., Huntley, George W.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222060/
https://ncbi.nlm.nih.gov/pubmed/30249796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1457-18.2018
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