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Origins of Parkinson’s Disease in Brain Development: Insights From Early and Persistent Effects of LRRK2-G2019S on Striatal Circuits

Late-onset Parkinson’s disease (PD) is dominated clinically and experimentally by a focus on dopamine neuron degeneration and ensuing motor system abnormalities. There are, additionally, a number of non-motor symptoms – including cognitive and psychiatric – that can appear much earlier in the course...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Huntley, George W., Benson, Deanna L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113397/
https://ncbi.nlm.nih.gov/pubmed/32273839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00265
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