LRRK2 mutation alters behavioral, synaptic, and nonsynaptic adaptations to acute social stress

Parkinson’s disease (PD) risk is increased by stress and certain gene mutations, including the most prevalent PD-linked mutation LRRK2-G2019S. Both PD and stress increase risk for psychiatric symptoms, yet it is unclear how PD-risk genes alter neural circuitry in response to stress that may promote...

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Dettagli Bibliografici
Pubblicato in:J Neurophysiol
Autori principali: Guevara, Christopher A., Matikainen-Ankney, Bridget A., Kezunovic, Nebojsa, LeClair, Katherine, Conway, Alexander P., Menard, Caroline, Flanigan, Meghan E., Pfau, Madeline, Russo, Scott J., Benson, Deanna L., Huntley, George W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
Soggetti:
Rapid Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311730/
https://ncbi.nlm.nih.gov/pubmed/32374202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00137.2020
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