The p53 C-Terminus Controls Site-Specific DNA Binding and Promotes Structural Changes within the Central DNA Binding Domain

DNA binding by numerous transcription factors including the p53 tumor suppressor protein constitutes a vital early step in transcriptional activation. While the role of the central core DNA binding domain (DBD) of p53 in site-specific DNA binding has been established, the contribution of the sequenc...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Laptenko, Oleg, Shiff, Idit, Freed-Pastor, Will, Zupnik, Andrew, Mattia, Melissa, Freulich, Ella, Shamir, Inbal, Kadouri, Noam, Kahn, Tamar, Manfredi, James, Simon, Itamar, Prives, Carol
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221458/
https://ncbi.nlm.nih.gov/pubmed/25794615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.015
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