ロード中...
The C-terminus of p53 binds the N-terminal domain of MDM2
The p53 tumor suppressor interacts with its negative regulator Mdm2 via the former’s N-terminal region and core domain. Yet the extreme p53 C-terminal region contains lysine residues ubiquitinated by Mdm2 and can bear post-translational modifications that inhibit Mdm2–p53 association. We show that,...
保存先:
| 主要な著者: | , , , , , , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922928/ https://ncbi.nlm.nih.gov/pubmed/20639885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1872 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|