Loading...
Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis
The mTOR inhibitor rapamycin ameliorates the clinical and biochemical phenotype of mouse, worm, and cellular models of mitochondrial disease, via an unclear mechanism. Here, we show that prolonged rapamycin treatment improved motor endurance, corrected morphological abnormalities of muscle, and incr...
Na minha lista:
| Udgivet i: | EMBO Mol Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6220341/ https://ncbi.nlm.nih.gov/pubmed/30309855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708799 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|