Perturbed Redox Signaling Exacerbates a Mitochondrial Myopathy

Alternative oxidases (AOXs) bypass respiratory complexes III and IV by transferring electrons from coenzyme Q directly to O(2). They have therefore been proposed as a potential therapeutic tool for mitochondrial diseases. We crossed the severely myopathic skeletal muscle-specific COX15 knockout (KO)...

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Foilsithe in:Cell Metab
Main Authors: Dogan, Sukru Anil, Cerutti, Raffaele, Benincá, Cristiane, Brea-Calvo, Gloria, Jacobs, Howard Trevor, Zeviani, Massimo, Szibor, Marten, Viscomi, Carlo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cell Press 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224544/
https://ncbi.nlm.nih.gov/pubmed/30122554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.07.012
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