Exosomal miR-99a-5p is elevated in sera of ovarian cancer patients and promotes cancer cell invasion by increasing fibronectin and vitronectin expression in neighboring peritoneal mesothelial cells

BACKGROUND: microRNAs (miRNAs) stably exist in circulating blood and are encapsulated in extracellular vesicles such as exosomes. The aims of this study were to identify which exosomal miRNAs are highly produced from epithelial ovarian cancer (EOC) cells, to analyze whether serum miRNA can be used t...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Yoshimura, Akihiko, Sawada, Kenjiro, Nakamura, Koji, Kinose, Yasuto, Nakatsuka, Erika, Kobayashi, Masaki, Miyamoto, Mayuko, Ishida, Kyoso, Matsumoto, Yuri, Kodama, Michiko, Hashimoto, Kae, Mabuchi, Seiji, Kimura, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217763/
https://ncbi.nlm.nih.gov/pubmed/30396333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4974-5
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