Exosomal miR-99a-5p is elevated in sera of ovarian cancer patients and promotes cancer cell invasion by increasing fibronectin and vitronectin expression in neighboring peritoneal mesothelial cells

BACKGROUND: microRNAs (miRNAs) stably exist in circulating blood and are encapsulated in extracellular vesicles such as exosomes. The aims of this study were to identify which exosomal miRNAs are highly produced from epithelial ovarian cancer (EOC) cells, to analyze whether serum miRNA can be used t...

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發表在:BMC Cancer
Main Authors: Yoshimura, Akihiko, Sawada, Kenjiro, Nakamura, Koji, Kinose, Yasuto, Nakatsuka, Erika, Kobayashi, Masaki, Miyamoto, Mayuko, Ishida, Kyoso, Matsumoto, Yuri, Kodama, Michiko, Hashimoto, Kae, Mabuchi, Seiji, Kimura, Tadashi
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217763/
https://ncbi.nlm.nih.gov/pubmed/30396333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4974-5
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