Plasminogen activator inhibitor-1 is an independent prognostic factor of ovarian cancer and IMD-4482, a novel plasminogen activator inhibitor-1 inhibitor, inhibits ovarian cancer peritoneal dissemination

In the present study, the therapeutic potential of targeting plasminogen activator inhibitor-1 (PAI-1) in ovarian cancer was tested. Tissues samples from 154 cases of ovarian carcinoma were immunostained with anti-PAI-1 antibody, and the prognostic value was analyzed. Among the samples, 67% (104/154...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nakatsuka, Erika, Sawada, Kenjiro, Nakamura, Koji, Yoshimura, Akihito, Kinose, Yasuto, Kodama, Michiko, Hashimoto, Kae, Mabuchi, Seiji, Makino, Hiroshi, Morii, Eiichi, Yamaguchi, Yoichi, Yanase, Takeshi, Itai, Akiko, Morishige, Ken-ichirou, Kimura, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685717/
https://ncbi.nlm.nih.gov/pubmed/29163796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20834
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