Exosomal miR-99a-5p is elevated in sera of ovarian cancer patients and promotes cancer cell invasion by increasing fibronectin and vitronectin expression in neighboring peritoneal mesothelial cells

BACKGROUND: microRNAs (miRNAs) stably exist in circulating blood and are encapsulated in extracellular vesicles such as exosomes. The aims of this study were to identify which exosomal miRNAs are highly produced from epithelial ovarian cancer (EOC) cells, to analyze whether serum miRNA can be used t...

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Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Yoshimura, Akihiko, Sawada, Kenjiro, Nakamura, Koji, Kinose, Yasuto, Nakatsuka, Erika, Kobayashi, Masaki, Miyamoto, Mayuko, Ishida, Kyoso, Matsumoto, Yuri, Kodama, Michiko, Hashimoto, Kae, Mabuchi, Seiji, Kimura, Tadashi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217763/
https://ncbi.nlm.nih.gov/pubmed/30396333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4974-5
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