RBTT-07. NUTMEG: A RANDOMISED PHASE II STUDY OF NIVOLUMAB AND TEMOZOLOMIDE (TMZ) VS TMZ ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM): TRIAL IN PROGRESS

BACKGROUND: An increase of mutations as we age is well documented in GBM and in cancer in general. Elderly patients with GBM may have higher mutational burden and may be more likely to respond to immunotherapies. NUTMEG is a randomised Phase II study comparing post radiation NivolUmab and TMZ versus...

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Vydáno v:Neuro Oncol
Hlavní autoři: Khasraw, Mustafa, McDonald, Kerrie, Yip, Sonia, Verhaak, Roel, Heimberger, Amy, Hall, Merryn, Fisher, Lauren, Barnes, Elizabeth, Rosenthal, Mark, Gedye, Craig, Hovey, Elizabeth, Ellingson, Benjamin, Simes, John, Tognela, Annette, Koh, Eng-Siew, Gan, Hui, Back, Michael, Lwin, Zarnie
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217643/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.976
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