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RBTT-07. NUTMEG: A RANDOMISED PHASE II STUDY OF NIVOLUMAB AND TEMOZOLOMIDE (TMZ) VS TMZ ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM): TRIAL IN PROGRESS

BACKGROUND: An increase of mutations as we age is well documented in GBM and in cancer in general. Elderly patients with GBM may have higher mutational burden and may be more likely to respond to immunotherapies. NUTMEG is a randomised Phase II study comparing post radiation NivolUmab and TMZ versus...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Khasraw, Mustafa, McDonald, Kerrie, Yip, Sonia, Verhaak, Roel, Heimberger, Amy, Hall, Merryn, Fisher, Lauren, Barnes, Elizabeth, Rosenthal, Mark, Gedye, Craig, Hovey, Elizabeth, Ellingson, Benjamin, Simes, John, Tognela, Annette, Koh, Eng-Siew, Gan, Hui, Back, Michael, Lwin, Zarnie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217643/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.976
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