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CBMT-45. A NOVEL C-CIRCLE ASSAY FOR DETECTING ALTERNATIVE LENGTHENING OF TELOMERES (ALT) MECHANISMS

Low-grade gliomas, in particular astrocytoma, have been previously reported to harbor Alternative lengthening of telomere (ALT) to maintain their telomeres to aid sustained replication. Targeting genetic pathways specific to ALT mechanism is crucial in developing novel drugs to minimise recurrence a...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Noor, Humaira, Rapkins, Robert, Henson, Jeremy, McDonald, Kerrie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217228/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.164
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