A C-circle assay for detection of alternative lengthening of telomere activity in FFPE tissue

Alternative lengthening of telomeres (ALT) is a telomerase-independent, recombination-based telomere maintenance mechanism that allows cancer cells to acquire unlimited proliferative capacity. The C-circle assay (CCA) has emerged as the gold standard for quantitative measurement of ALT activity. Her...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:STAR Protoc
Egile Nagusiak: Idilli, Aurora I., Segura-Bayona, Sandra, Lippert, Timothy P., Boulton, Simon J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2021
Gaiak:
Protocol
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8182116/
https://ncbi.nlm.nih.gov/pubmed/34136834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100569
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