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Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
To achieve replicative immortality, cancer cells must activate telomere maintenance mechanisms to prevent telomere shortening. ~85% of cancers circumvent telomeric attrition by re-expressing telomerase, while the remaining ~15% of cancers induce alternative lengthening of telomeres (ALT), which reli...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7820467/ https://ncbi.nlm.nih.gov/pubmed/33479235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20819-4 |
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