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TMOD-19. MUTANT IDH1 PROMOTES GLIOMA FORMATION IN VIVO

Gliomas are the most common primary central nervous system tumor but the molecular mechanisms responsible for their development and progression are not completely understood. Isocitrate dehydrogenase 1 (IDH1) is the most commonly mutated gene in grade II-III glioma and secondary glioblastoma (GBM) b...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Yu, Diana, Boekholder, Ryan, VanBrocklin, Matthew, Sonnen, Joshua, Colman, Howard, Holmen, Sheri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216632/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1131
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