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CSIG-10. INVESTIGATING THE S6K1 AND S6K2 IN PTEN-DEFICIENT GLIOBLASTOMA
BACKGROUND: Glioblastoma (GBM), the most lethal type of malignant brain cancer in adults, sustains frequent mutations and/or deletions in the tumor suppressor gene PTEN (phosphatase and tensin homolog), resulting in the activation of downstream mTOR-S6K signaling. METHODS: We proposed experiments to...
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| Publicat a: | Neuro Oncol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216614/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.176 |
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