O6.10 GLIOMA CELL VEGFR-2 EXPRESSION IMPAIRS CHEMOTHERAPEUTIC AND ANTIANGIOGENIC TREATMENTS IN PTEN-DEFICIENT GLIOBLASTOMA

BACKGROUND: Given the recent failure of bevacizumab (BEV) in extending overall survival of patients with newly diagnosed glioblastoma, tissue biomarkers predicting response to antiangiogenic treatments are urgently needed. Here, we hypothesized that loss of the tumor suppressor phosphatase and tensi...

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Hlavní autoři: Weiler, M., Kessler, T., Sahm, F., Blaes, J., Osswald, M., Milford, D., Urban, S., Ruiz de Almodóvar, C., Heiland, S., Wick, W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Oral Presentations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185819/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.51
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