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Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma
Glioblastoma multiforme (GBM) can present as either de novo or secondary tumors arising from previously diagnosed low-grade gliomas. Although these tumor types are phenotypically indistinguishable, de novo and secondary GBMs are associated with distinct genetic characteristics. PTEN mutations, which...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Duke University Press
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1907411/ https://ncbi.nlm.nih.gov/pubmed/17504928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2007-003 |
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