DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression

We explored the associations of aberrant DNA methylation patterns in 12 candidate genes with adult glioma subtype, patient survival, and gene expression of enhancer of zeste human homolog 2 (EZH2) and insulin-like growth factor-binding protein 2 (IGFBP2). We analyzed 154 primary glioma tumors (37 as...

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Hlavní autoři: Zheng, Shichun, Houseman, E. Andres, Morrison, Zachary, Wrensch, Margaret R., Patoka, Joseph S., Ramos, Christian, Haas-Kogan, Daphne A., McBride, Sean, Marsit, Carmen J., Christensen, Brock C., Nelson, Heather H., Stokoe, David, Wiemels, Joseph L., Chang, Susan M., Prados, Michael D., Tihan, Tarik, Vandenberg, Scott R., Kelsey, Karl T., Berger, Mitchel S., Wiencke, John K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064601/
https://ncbi.nlm.nih.gov/pubmed/21339190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq190
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