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ACTR-36. A SINGLE ARM PHASE 2 STUDY OF THE DUAL mTORC1/mTORC2 INHIBITOR VISTUSERTIB PROVIDED ON AN INTERMITTENT SCHEDULE FOR NEUROFIBROMATOSIS 2 PATIENTS WITH PROGRESSIVE OR SYMPTOMATIC MENINGIOMAS
Meningiomas are the second most common tumor in NF2 patients, with a cumulative prevalence of 80% by age 70 and a high prevalence of multiple meningiomas. Surgery remains standard of care for these tumors, yet outcomes remain suboptimal for many patients with multiple tumors. Loss of NF2 expression...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216352/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.069 |
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