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mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma
BACKGROUND: Neurofibromatosis type 2 (NF2) is a rare autosomal dominant genetic disorder, resulting in a variety of neural tumors, with bilateral vestibular schwannomas as the most frequent manifestation. Recently, merlin, the NF2 tumor suppressor, has been identified as a novel negative regulator o...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3956353/ https://ncbi.nlm.nih.gov/pubmed/24414536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not242 |
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