ACTR-36. A SINGLE ARM PHASE 2 STUDY OF THE DUAL mTORC1/mTORC2 INHIBITOR VISTUSERTIB PROVIDED ON AN INTERMITTENT SCHEDULE FOR NEUROFIBROMATOSIS 2 PATIENTS WITH PROGRESSIVE OR SYMPTOMATIC MENINGIOMAS

Meningiomas are the second most common tumor in NF2 patients, with a cumulative prevalence of 80% by age 70 and a high prevalence of multiple meningiomas. Surgery remains standard of care for these tumors, yet outcomes remain suboptimal for many patients with multiple tumors. Loss of NF2 expression...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Plotkin, Scott, Jordan, Justin, Beauchamp, Roberta, Muzikansky, Alona, Stemmer-Rachamimov, Anat, Ramesh, Vijaya
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216352/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.069
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