載入...
EXTH-64. IMIPRIDONES CAUSE METABOLIC REPROGRAMMING AND ELICIT UNIQUE VULNERABILITIES IN PRECLINICAL MODEL SYSTEMS OF GLIOBLASTOMA
The purpose of this study is to improve the efficacy of imipridones, a novel class of AKT/ERK inhibitors. The lead compound ONC201 has entered clinical testing for glioblastoma (GBM) and recently chemically modified imipridones, ONC206 and ONC212, have been designed. Transcriptome, untargeted liquid...
Na minha lista:
| 發表在: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2018
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216202/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.411 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|