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Tumor suppressive role for kinases phosphorylating p53 in DNA damage‐induced apoptosis
Tumor suppressor p53 plays an important role in cancer prevention. Under normal conditions, p53 is maintained at a low level. However, in response to various cellular stresses, p53 is stabilized and activated, which, in turn, initiates DNA repair, cell‐cycle arrest, senescence and apoptosis. Post‐tr...
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| Pubblicato in: | Cancer Sci |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6215896/ https://ncbi.nlm.nih.gov/pubmed/30191640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13792 |
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