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Protein kinase Cδ is responsible for constitutive and DNA damage-induced phosphorylation of Rad9

The mammalian homolog of the Schizosaccharomyces pombe Rad9 is involved in checkpoint signaling and the induction of apoptosis. While the mechanisms responsible for the regulation of human Rad9 (hRad9) are not known, hRad9 is subject to hyperphosphorylation in the response of cells to DNA damage. Th...

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Bibliographic Details
Main Authors: Yoshida, Kiyotsugu, Wang, Hong-Gang, Miki, Yoshio, Kufe, Donald
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC151076/
https://ncbi.nlm.nih.gov/pubmed/12628935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg134
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