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Protein Kinase C δ Activates Topoisomerase IIα To Induce Apoptotic Cell Death in Response to DNA Damage
DNA topoisomerase II is an essential nuclear enzyme that modulates DNA processes by altering the topological state of double-stranded DNA. This enzyme is required for chromosome condensation and segregation; however, the regulatory mechanism of its activation is largely unknown. Here we demonstrate...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2006
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1447416/ https://ncbi.nlm.nih.gov/pubmed/16611985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.9.3414-3431.2006 |
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