MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents

The TAM (TYRO-3, AXL, MERTK) family receptor tyrosine kinases (RTKs) play an important role in promoting growth, survival, and metastatic spread of several tumor types. AXL and MERTK are overexpressed in head and neck squamous cell carcinoma (HNSCC), triple-negative breast cancer (TNBC), and non-sma...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cancer Ther
Auteurs principaux: McDaniel, Nellie K., Cummings, Christopher T., Iida, Mari, Hülse, Justus, Pearson, Hannah E., Vasileiadi, Eleana, Parker, Rebecca E., Orbuch, Rachel A., Ondracek, Olivia J., Welke, Noah B., Kang, Grace Hye-Hyun, Davies, Kurtis D., Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Harari, Paul M., Kimple, Randall J., DeRyckere, Deborah, Graham, Douglas K., Wheeler, Deric L.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215511/
https://ncbi.nlm.nih.gov/pubmed/30093568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1239
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires