MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents

The TAM (TYRO-3, AXL, MERTK) family receptor tyrosine kinases (RTKs) play an important role in promoting growth, survival, and metastatic spread of several tumor types. AXL and MERTK are overexpressed in head and neck squamous cell carcinoma (HNSCC), triple-negative breast cancer (TNBC), and non-sma...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Ther
Asıl Yazarlar: McDaniel, Nellie K., Cummings, Christopher T., Iida, Mari, Hülse, Justus, Pearson, Hannah E., Vasileiadi, Eleana, Parker, Rebecca E., Orbuch, Rachel A., Ondracek, Olivia J., Welke, Noah B., Kang, Grace Hye-Hyun, Davies, Kurtis D., Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Harari, Paul M., Kimple, Randall J., DeRyckere, Deborah, Graham, Douglas K., Wheeler, Deric L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215511/
https://ncbi.nlm.nih.gov/pubmed/30093568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1239
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