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Ascorbic acid inhibits senescence in mesenchymal stem cells through ROS and AKT/mTOR signaling

Mesenchymal stem cell (MSC) aging seriously affects its function in stem cell transplantation for treatment. Extensive studies have focused on how to inhibit senescence in MSCs. However, the mechanism of senescence in MSC was not clear. In this study, we used d-galactose to induce MSC aging. Then we...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Yang, Mengkai, Teng, Songsong, Ma, Chunhui, Yu, Yinxian, Wang, Peilin, Yi, Chengqing
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214856/
https://ncbi.nlm.nih.gov/pubmed/29777434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-018-0220-x
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