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Ascorbic acid inhibits senescence in mesenchymal stem cells through ROS and AKT/mTOR signaling

Mesenchymal stem cell (MSC) aging seriously affects its function in stem cell transplantation for treatment. Extensive studies have focused on how to inhibit senescence in MSCs. However, the mechanism of senescence in MSC was not clear. In this study, we used d-galactose to induce MSC aging. Then we...

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Podrobná bibliografie
Vydáno v:Cytotechnology
Hlavní autoři: Yang, Mengkai, Teng, Songsong, Ma, Chunhui, Yu, Yinxian, Wang, Peilin, Yi, Chengqing
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214856/
https://ncbi.nlm.nih.gov/pubmed/29777434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-018-0220-x
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