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Molecular mechanisms for dynamic regulation of N1 riboswitch by aminoglycosides
A synthetic riboswitch N1, inserted into the 5′-untranslated mRNA region of yeast, regulates gene expression upon binding ribostamycin and neomycin. Interestingly, a similar aminoglycoside, paromomycin, differing from neomycin by only one substituent (amino versus hydroxyl), also binds to the N1 rib...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6212780/ https://ncbi.nlm.nih.gov/pubmed/30239867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky833 |
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