Wird geladen...

Multi-Scale Flexible Fitting of Proteins to Cryo-EM Density Maps at Medium Resolution

Structure determination using cryo-electron microscopy (cryo-EM) medium-resolution density maps is often facilitated by flexible fitting. Avoiding overfitting, adjusting force constants driving the structure to the density map, and emulating complex conformational transitions are major concerns in t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Mol Biosci
Hauptverfasser: Kulik, Marta, Mori, Takaharu, Sugita, Yuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025875/
https://ncbi.nlm.nih.gov/pubmed/33842541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.631854
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!