Electrostatic Interactions in Aminoglycoside-RNA Complexes

Electrostatic interactions often play key roles in the recognition of small molecules by nucleic acids. An example is aminoglycoside antibiotics, which by binding to ribosomal RNA (rRNA) affect bacterial protein synthesis. These antibiotics remain one of the few valid treatments against hospital-acq...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Kulik, Marta, Goral, Anna M., Jasiński, Maciej, Dominiak, Paulina M., Trylska, Joanna
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2015
Teme:
Proteins and Nucleic Acids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317553/
https://ncbi.nlm.nih.gov/pubmed/25650932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.020
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