A carregar...
Abrogating native α-synuclein tetramers in mice causes a L-DOPA responsive motor syndrome closely resembling Parkinson’s disease
α-Synuclein (αS) regulates vesicle exocytosis but forms insoluble deposits in Parkinson’s disease. Developing disease-modifying therapies requires animal models that reproduce cardinal features of PD. We recently described a previously unrecognized physiological form of αS, α-helical tetramers, and...
Na minha lista:
| Publicado no: | Neuron |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6211795/ https://ncbi.nlm.nih.gov/pubmed/30308173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.09.014 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|