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High-throughput characterization of genetic effects on DNA–protein binding and gene transcription
Many variants associated with complex traits are in noncoding regions and contribute to phenotypes by disrupting regulatory sequences. To characterize these variants, we developed a streamlined protocol for a high-throughput reporter assay, Biallelic Targeted STARR-seq (BiT-STARR-seq), that identifi...
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| Yayımlandı: | Genome Res |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6211638/ https://ncbi.nlm.nih.gov/pubmed/30254052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.237354.118 |
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