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Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding?

Large experimental efforts are characterizing the regulatory genome, yet we are still missing a systematic definition of functional and silent genetic variants in non-coding regions. Here, we integrated DNaseI footprinting data with sequence-based transcription factor (TF) motif models to predict th...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Moyerbrailean, Gregory A., Kalita, Cynthia A., Harvey, Chris T., Wen, Xiaoquan, Luca, Francesca, Pique-Regi, Roger
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764260/
https://ncbi.nlm.nih.gov/pubmed/26901046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005875
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