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Comparative evaluation of DNase-seq footprint identification strategies

DNase I is an enzyme preferentially cleaving DNA in highly accessible regions. Recently, Next-Generation Sequencing has been applied to DNase I assays (DNase-seq) to obtain genome-wide maps of these accessible chromatin regions. With high-depth sequencing, DNase I cleavage sites can be identified wi...

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Detalhes bibliográficos
Main Authors: Barozzi, Iros, Bora, Pranami, Morelli, Marco J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133688/
https://ncbi.nlm.nih.gov/pubmed/25177346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00278
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