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QuASAR-MPRA: accurate allele-specific analysis for massively parallel reporter assays

MOTIVATION: The majority of the human genome is composed of non-coding regions containing regulatory elements such as enhancers, which are crucial for controlling gene expression. Many variants associated with complex traits are in these regions, and may disrupt gene regulatory sequences. Consequent...

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Bibliografski detalji
Izdano u:Bioinformatics
Glavni autori: Kalita, Cynthia A, Moyerbrailean, Gregory A, Brown, Christopher, Wen, Xiaoquan, Luca, Francesca, Pique-Regi, Roger
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049023/
https://ncbi.nlm.nih.gov/pubmed/29028988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx598
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