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QuASAR-MPRA: accurate allele-specific analysis for massively parallel reporter assays
MOTIVATION: The majority of the human genome is composed of non-coding regions containing regulatory elements such as enhancers, which are crucial for controlling gene expression. Many variants associated with complex traits are in these regions, and may disrupt gene regulatory sequences. Consequent...
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| Publié dans: | Bioinformatics |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6049023/ https://ncbi.nlm.nih.gov/pubmed/29028988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx598 |
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