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QuASAR-MPRA: accurate allele-specific analysis for massively parallel reporter assays

MOTIVATION: The majority of the human genome is composed of non-coding regions containing regulatory elements such as enhancers, which are crucial for controlling gene expression. Many variants associated with complex traits are in these regions, and may disrupt gene regulatory sequences. Consequent...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Kalita, Cynthia A, Moyerbrailean, Gregory A, Brown, Christopher, Wen, Xiaoquan, Luca, Francesca, Pique-Regi, Roger
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049023/
https://ncbi.nlm.nih.gov/pubmed/29028988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx598
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