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High-throughput characterization of genetic effects on DNA–protein binding and gene transcription
Many variants associated with complex traits are in noncoding regions and contribute to phenotypes by disrupting regulatory sequences. To characterize these variants, we developed a streamlined protocol for a high-throughput reporter assay, Biallelic Targeted STARR-seq (BiT-STARR-seq), that identifi...
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| Publicado no: | Genome Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6211638/ https://ncbi.nlm.nih.gov/pubmed/30254052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.237354.118 |
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