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ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data

BACKGROUND: Although human leukocyte antigen (HLA) genotyping based on amplicon, whole exome sequence (WES), and RNA sequence data has been achieved in recent years, accurate genotyping from whole genome sequence (WGS) data remains a challenge due to the low depth. Furthermore, there is no method to...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Hayashi, Shuto, Yamaguchi, Rui, Mizuno, Shinichi, Komura, Mitsuhiro, Miyano, Satoru, Nakagawa, Hidewaki, Imoto, Seiya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211482/
https://ncbi.nlm.nih.gov/pubmed/30384854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5169-9
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