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A Bayesian model integration for mutation calling through data partitioning

MOTIVATION: Detection of somatic mutations from tumor and matched normal sequencing data has become among the most important analysis methods in cancer research. Some existing mutation callers have focused on additional information, e.g. heterozygous single-nucleotide polymorphisms (SNPs) nearby mut...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Moriyama, Takuya, Imoto, Seiya, Hayashi, Shuto, Shiraishi, Yuichi, Miyano, Satoru, Yamaguchi, Rui
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821361/
https://ncbi.nlm.nih.gov/pubmed/30924874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz233
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