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HapMuC: somatic mutation calling using heterozygous germ line variants near candidate mutations
Motivation: Identifying somatic changes from tumor and matched normal sequences has become a standard approach in cancer research. More specifically, this requires accurate detection of somatic point mutations with low allele frequencies in impure and heterogeneous cancer samples. Although haplotype...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816033/ https://ncbi.nlm.nih.gov/pubmed/25123903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu537 |
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