HapMuC: somatic mutation calling using heterozygous germ line variants near candidate mutations

Motivation: Identifying somatic changes from tumor and matched normal sequences has become a standard approach in cancer research. More specifically, this requires accurate detection of somatic point mutations with low allele frequencies in impure and heterogeneous cancer samples. Although haplotype...

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Bibliografiska uppgifter
I publikationen:Bioinformatics
Huvudupphovsmän: Usuyama, Naoto, Shiraishi, Yuichi, Sato, Yusuke, Kume, Haruki, Homma, Yukio, Ogawa, Seishi, Miyano, Satoru, Imoto, Seiya
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Original Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816033/
https://ncbi.nlm.nih.gov/pubmed/25123903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu537
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