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A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures

Recent advances in sequencing technologies have enabled the production of massive amounts of data on somatic mutations from cancer genomes. These data have led to the detection of characteristic patterns of somatic mutations or “mutation signatures” at an unprecedented resolution, with the potential...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Shiraishi, Yuichi, Tremmel, Georg, Miyano, Satoru, Stephens, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667891/
https://ncbi.nlm.nih.gov/pubmed/26630308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005657
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